FEM1B antibody (C-Term)
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- Target See all FEM1B Antibodies
- FEM1B (Fem-1 Homolog B (FEM1B))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FEM1B antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Purification
- F1A alpha Antibody is affinity chromatography purified via peptide column.
- Immunogen
- F1A antibody was raised against a 14 amino acid peptide near the carboxy terminus of human F1A. The immunogen is located within the last 50 amino acids of F1A alpha.
- Isotype
- IgG
- Top Product
- Discover our top product FEM1B Primary Antibody
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- Application Notes
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F1Ab antibody can be used for detection of F1Ab by Western blot at 1 μ,g/mL. An approximately 70 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse and rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- F1A alpha Antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- F1A alpha antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- FEM1B (Fem-1 Homolog B (FEM1B))
- Alternative Name
- F1A alpha (FEM1B Products)
- Synonyms
- F1A-ALPHA antibody, F1AA antibody, FEM1-beta antibody, FEM1B antibody, mKIAA0396 antibody, fem-1 homolog B antibody, protein fem-1 homolog B antibody, fem-1 homolog B L homeolog antibody, fem-1 homolog b (C. elegans) antibody, feminization 1 homolog b (C. elegans) antibody, FEM1B antibody, Fem1b antibody, LOC413692 antibody, fem1b.L antibody, fem1b antibody
- Background
- F1A alpha Antibody: Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1β,. F1Aalpha/FEM1β, is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aalpha is cleaved by CED-3 and caspase. FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1. Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues.
- Molecular Weight
- 70 kDa
- Gene ID
- 10116
- UniProt
- Q9UK73
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