IL32 antibody (C-Term)

Catalog No. ABIN6990630

Product Details anti-IL32 Antibody

Target: IL32 (Interleukin 32 (IL32))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL32 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: This antibody detects all isoforms of IL-32.

Purification: IL-32 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-IL-32 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human IL-32. The immunogen is located within the last 50 amino acids of IL-32.

Isotype: IgG

Application Details

Application Notes: WB: 0.5-4 μ,g/mL, IHC: 2-10 μ,g/mL, IF: 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human and mouse samples, Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-32 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: IL-32 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for IL32

Target: IL32 (Interleukin 32 (IL32))

Alternative Name: IL-32 (IL32 Products)

Synonyms: IL-32alpha antibody, IL-32beta antibody, IL-32delta antibody, IL-32gamma antibody, NK4 antibody, TAIF antibody, TAIFa antibody, TAIFb antibody, TAIFc antibody, TAIFd antibody, interleukin 32 antibody, IL32 antibody

Background: IL-32 Antibody: Interleukin-32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2. It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32. IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. Because treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-α, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFNγ, it has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis.

Molecular Weight: Predicted: 26kD

Observed: 26 kD kDa

Gene ID: 9235

UniProt: P24001