SLITRK3 antibody (C-Term)

Catalog No. ABIN6990854

Product Details anti-SLITRK3 Antibody

Target: SLITRK3 (SLIT and NTRK-Like Family, Member 3 (SLITRK3))

Binding Specificity: AA 320-370, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLITRK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: This antibody is predicted to have no cross-reactivity to other Slitrk proteins.

Purification: Slitrk3 Antibody is affinity chromatography purified via peptide column.

Immunogen: Slitrk3 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Slitrk3. The immunogen is located within amino acids 320 - 370 of Slitrk3.

Isotype: IgG

Application Details

Application Notes: Slitrk3 antibody can be used for detection of Slitrk3 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Slitrk3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Slitrk3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SLITRK3

Target: SLITRK3 (SLIT and NTRK-Like Family, Member 3 (SLITRK3))

Alternative Name: Slitrk3 (SLITRK3 Products)

Synonyms: SLIT and NTRK-like family, member 3 antibody, SLIT and NTRK like family member 3 antibody, SKI like proto-oncogene antibody, Slitrk3 antibody, SLITRK3 antibody, slitrk3 antibody, SKIL antibody

Background: Slitrk3 Antibody: SLIT and NTRK-like family 3 (Slitrk3) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk3 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.

Gene ID: 22865

UniProt: O94933