APBA1 antibody

Catalog No. ABIN6990910

Product Details anti-APBA1 Antibody

Target: APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APBA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: UROP11 Antibody is affinity chromatography purified via peptide column.

Immunogen: UROP11 antibody was raised against a 12 amino acid synthetic peptide near the center of the mouse UROP11. The immunogen is located within the first 50 amino acids of UROP11.

Isotype: IgG

Application Details

Application Notes: UROP11 antibody can be used for detection of UROP11 by Western blot at 1 - 2 μ,g/mL. Despite its predicted molecular weight, UROP11 often migrates at a much higher apparent size in SDS-PAGE.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: UROP11 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: UROP11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for APBA1

Target: APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))

Alternative Name: UROP11 (APBA1 Products)

Synonyms: APBA1 antibody, 6430513E09Rik antibody, Lin-10 antibody, Mint antibody, Mint1 antibody, Urop11 antibody, X11 antibody, X11alpha antibody, D9S411E antibody, LIN10 antibody, MINT1 antibody, X11A antibody, X11ALPHA antibody, amyloid beta precursor protein binding family A member 1 antibody, amyloid beta (A4) precursor protein-binding, family A, member 1b antibody, ketopantoate reductase antibody, 2-dehydropantoate 2-reductase antibody, amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) antibody, amyloid beta (A4) precursor protein-binding, family A, member 1 antibody, amyloid beta (A4) precursor protein binding, family A, member 1 antibody, APBA1 antibody, apba1b antibody, apbA1 antibody, apba1 antibody, Apba1 antibody

Background: UROP11 Antibody: Upregulated obese product 11 (UROP11) was isolated from subtractive library for mouse hypothalamus. It is detected in numerous tissues and is upregulated in the hypothalamus and adipocytes in obese mice. UROP11 is also observed in human neural and lymphoid tissues, its expression appears to be regulated by the level of lymphoid activation. Urop11 expression is strongly upregulated both in vivo in mouse hypothalamus and in vitro in mouse neural cell lines after treatment with leptin, indicating Urop11 is a target of leptin activity and thus may play a role in obesity.

Gene ID: 319924

UniProt: B2RUJ5

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport