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TRIM30 antibody (C-Term)

Trim30 Reactivity: Mouse WB, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6990955
  • Target See all TRIM30 (Trim30) Antibodies
    TRIM30 (Trim30) (Tripartite Motif Containing 30 (Trim30))
    Binding Specificity
    • 2
    • 1
    • 1
    AA 250-300, C-Term
    Reactivity
    • 3
    • 2
    • 2
    Mouse
    Host
    • 3
    Rabbit
    Clonality
    • 3
    Polyclonal
    Conjugate
    • 3
    This TRIM30 antibody is un-conjugated
    Application
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    TRIM30 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    TRIM30 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of the mouse TRIM30. The immunogen is located within amino acids 250 - 300 of TRIM30.
    Isotype
    IgG
    Top Product
    Discover our top product Trim30 Primary Antibody
  • Application Notes
    TRIM30 antibody can be used for detection of TRIM30 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    TRIM30 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    TRIM30 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    TRIM30 (Trim30) (Tripartite Motif Containing 30 (Trim30))
    Alternative Name
    TRIM30 (Trim30 Products)
    Synonyms
    RGD1563970 antibody, Rpt-1 antibody, Rpt1 antibody, Trim30 antibody, tripartite motif-containing 30 antibody, tripartite motif-containing 30A antibody, Trim30 antibody, Trim30a antibody
    Background
    TRIM30 Antibody: TRIM30 belongs to a family of the tripartite motif (TRIM) proteins involved in the regulation of cell proliferation, differentiation, development, oncogenesis, apoptosis and antiviral responses. The TRIM protein family is an expanding family of RING ('really interesting new gene') proteins, also known as RBCC proteins as they contain an RBCC motif, which comprises a RING domain, one or two B-boxes and a predicted coiled-coil region. Studies have shown that some TRIM family members are critical to innate immunity, TRIM5, TRIM19 and TRIM25, for example, have been shown to restrict viral infection. A recent study shows that TRIM30 functions as a negative modulator of the TLR signaling pathway, by targeting TAB2 and TAB3, and contributes to the inhibition of TLR-mediated NF-κ,B activation. The importance of TRIM30 in the attenuation or termination of NF-κ,B activation suggests that targeting of TAB2 and TAB3 by TRIM30α, may be a mechanism for modulating many types of immune responses.
    Gene ID
    20128
    NCBI Accession
    NP_033125
    UniProt
    P15533
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