ALDH3A1 antibody (C-Term)

Catalog No. ABIN6990972

Product Details anti-ALDH3A1 Antibody

Target: ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH3A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: At least two isoforms of Aldh3A1 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A2.

Purification: Aldh3A1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Aldh3A1 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human Aldh3A1. The immunogen is located within the last 50 amino acids of Aldh3A1.

Isotype: IgG

Application Details

Application Notes: Aldh3A1 antibody can be used for detection of Aldh3A1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Aldh3A1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Aldh3A1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ALDH3A1

Target: ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))

Alternative Name: Aldh3A1 (ALDH3A1 Products)

Synonyms: ALDC antibody, ALDH-E1 antibody, ALDH1 antibody, ALDH11 antibody, PUMB1 antibody, RALDH1 antibody, ALDH3 antibody, ALDHIII antibody, Ahd-4 antibody, Ahd4 antibody, Aldh antibody, Aldh3 antibody, AHDC antibody, Ahd-c antibody, aldehyde dehydrogenase 1 family member A1 antibody, aldehyde dehydrogenase 3 family member A1 antibody, aldehyde dehydrogenase antibody, aldehyde dehydrogenase, dimeric NADP-preferring antibody, aldehyde dehydrogenase family 3, subfamily A1 antibody, aldehyde dehydrogenase 3 family, member A1 antibody, ALDH1A1 antibody, ALDH3A1 antibody, OE_RS03630 antibody, LOC100077088 antibody, CLL_A1665 antibody, LOC100281700 antibody, LOC100285809 antibody, Aldh3a1 antibody

Background: Aldh3A1 Antibody: Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50 % of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorbtion of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice, mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1.

Gene ID: 218

NCBI Accession: NP_000682

UniProt: P30838