ATOH8 antibody (C-Term)
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- Target See all ATOH8 Antibodies
- ATOH8 (Atonal Homolog 8 (ATOH8))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ATOH8 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- ATOH8 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- ATOH8 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ATOH8. The immunogen is located within the last 50 amino acids of ATOH8.
- Isotype
- IgG
- Top Product
- Discover our top product ATOH8 Primary Antibody
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- Application Notes
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ATOH8 antibody can be used for detection of ATOH8 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- ATOH8 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- ATOH8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- ATOH8 (Atonal Homolog 8 (ATOH8))
- Alternative Name
- ATOH8 (ATOH8 Products)
- Synonyms
- ath6 antibody, zgc:158314 antibody, ATOH8 antibody, HATH6 antibody, bHLHa21 antibody, 4933425C05Rik antibody, Hath6 antibody, Math6 antibody, okadin antibody, RGD1561512 antibody, atonal bHLH transcription factor 8 antibody, atoh8 antibody, ATOH8 antibody, Atoh8 antibody
- Background
- ATOH8 Antibody: Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. ATOH8 (MATH6) is a tissue-restricted member of the atonal superfamily of bHLH transcription factors that exhibits 43-57 % identity in the bHLH domain with other mammalian atonal paralogs including the NeuroD and Neurogenin factors. In the mouse, ATOH8 has been implicated in the specification and differentiation of neuronal cell lineages in the brain and may also participate in kidney development. Recent studies show that ATOH8 is a novel component of the pancreatic transcriptional network during embryonic development and suggest a potential role as a modulator of the differentiation program initiated by the pro-endocrine factor Neurog3. It is indispensable for early embryonic development, suggesting a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes.
- Molecular Weight
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Predicted: 35 kDa
Observed: 40 kDa - Gene ID
- 84913
- NCBI Accession
- NP_116216
- UniProt
- Q96SQ7
- Pathways
- Regulation of Muscle Cell Differentiation
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