ZBED1 antibody (AA 180-230)

Catalog No. ABIN6991091

Product Details anti-ZBED1 Antibody

Target: ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))

Binding Specificity: AA 180-230

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBED1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: This antibody is predicted to have no cross-reactivity to ZBED2 or ZBED3.

Purification: ZBED1 Antibody is affinity chromatography purified via peptide column.

Immunogen: ZBED1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human ZBED1. The immunogen is located within amino acids 180 - 230 of ZBED1.

Isotype: IgG

Application Details

Application Notes: ZBED1 antibody can be used for detection of ZBED1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZBED1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ZBED1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ZBED1

Target: ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))

Alternative Name: ZBED1 (ZBED1 Products)

Synonyms: ZBED1 antibody, ZBED1P antibody, ALTE antibody, DREF antibody, TRAMP antibody, hDREF antibody, zinc finger BED-type containing 1 antibody, zinc finger, BED-type containing 1 antibody, ZBED1 antibody, zbed1 antibody

Background: ZBED1 Antibody: ZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation. RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in the inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting that ZBED1 also plays a role in cell proliferation in human cells. At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters, anti-ZBED1 RNAi also resulted in decreased RP gene expression. Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, and this self-association is required for nuclear localization and DNA binding.

Gene ID: 9189

UniProt: O96006