NDUFAF2 antibody (C-Term)

Catalog No. ABIN6991207

Product Details anti-NDUFAF2 Antibody

Target: NDUFAF2 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 2 (NDUFAF2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFAF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purification: Mimitin Antibody is affinity chromatography purified via peptide column.

Immunogen: Mimitin antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Mimitin. The immunogen is located within the last 50 amino acids of Mimitin.

Isotype: IgG

Application Details

Application Notes: Mimitin antibody can be used for detection of Mimitin by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunoflourescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Mimitin Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Mimitin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NDUFAF2

Target: NDUFAF2 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 2 (NDUFAF2))

Alternative Name: Mimitin (NDUFAF2 Products)

Synonyms: B17.2L antibody, MMTN antibody, NDUFA12L antibody, mimitin antibody, Ndufa12l antibody, RGD1560158 antibody, NDUFAF2 antibody, ndufa12l antibody, zgc:101036 antibody, 1810058I14Rik antibody, C86051 antibody, NADH:ubiquinone oxidoreductase complex assembly factor 2 antibody, NADH:ubiquinone oxidoreductase complex assembly factor 2 L homeolog antibody, NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 antibody, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2 antibody, NDUFAF2 antibody, Ndufaf2 antibody, ndufaf2.L antibody, ndufaf2 antibody

Background: Mimitin Antibody: Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80 % of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-κ,B-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.

Gene ID: 91942

NCBI Accession: NP_777549

UniProt: Q8N183

Pathways: SARS-CoV-2 Protein Interactome