NLRP13 antibody (N-Term)

Catalog No. ABIN6991409

Product Details anti-NLRP13 Antibody

Target: NLRP13 (NLR Family, Pyrin Domain Containing 13 (NLRP13))

Binding Specificity: AA 150-200, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Purification: NALP13 Antibody is affinity chromatography purified via peptide column.

Immunogen: NALP13 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NALP13. The immunogen is located within amino acids 150 - 200 of NALP13.

Isotype: IgG

Application Details

Application Notes: NALP13 antibody can be used for detection of NALP13 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: NALP13 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: NALP13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NLRP13

Target: NLRP13 (NLR Family, Pyrin Domain Containing 13 (NLRP13))

Alternative Name: NALP13 (NLRP13 Products)

Synonyms: CLR19.7 antibody, NALP13 antibody, NOD14 antibody, PAN13 antibody, NLR family pyrin domain containing 13 antibody, NLRP13 antibody

Background: NALP13 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.

Gene ID: 126204

UniProt: Q86W25

Pathways: Inflammasome