TRIP6 antibody (AA 190-240)

Catalog No. ABIN6991423

Product Details anti-TRIP6 Antibody

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Binding Specificity: AA 190-240

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Purification: TRIP6 Antibody is affinity chromatography purified via peptide column.

Immunogen: TRIP6 antibody was raised against a 15 amino acid synthetic peptide near the center of human TRIP6. The immunogen is located within amino acids 190 - 240 of TRIP6.

Isotype: IgG

Application Details

Application Notes: TRIP6 antibody can be used for detection of TRIP6 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TRIP6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TRIP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TRIP6

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Alternative Name: TRIP6 (TRIP6 Products)

Synonyms: TRIP6 antibody, OIP-1 antibody, OIP1 antibody, TRIP-6 antibody, TRIP6i2 antibody, ZRP-1 antibody, thyroid hormone receptor interactor 6 antibody, TRIP6 antibody, Trip6 antibody

Background: TRIP6 Antibody: TRIP6 (Thyroid receptor interacting protein 6) is a zyxin-related focal adhesion molecule involved in cell motility and antiapoptotic responses. TRIP6 is predominantly expressed in kidney, liver and lung. It has three LIM domains, a PDZ-binding motif, a Crk SH2-binding motif and/or other protein interacting domains. TRIP6 regulates NF-κ,B activation and interacts with RICK and TRAF2, proteins that are involved in TNF signaling. TRIP6 antagonizes Fas-induced apoptosis and promotes Fas-mediated cell migration in apoptosis-resistant glioma cells via Src-dependent phosphorylation of TRIP6 at Tyr-55.

Gene ID: 7205

NCBI Accession: NP_003293

UniProt: Q15654

Pathways: Cell-Cell Junction Organization