CXXC5 antibody (N-Term)

Catalog No. ABIN6991464

Product Details anti-CXXC5 Antibody

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Binding Specificity: AA 30-80, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXXC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: At least two isoforms of CXXC5 are known to exist. CXXC5 antibody is predicted to not cross-react with other CXXC protein family members.

Purification: CXXC5 Antibody is affinity chromatography purified via peptide column.

Immunogen: CXXC5 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CXXC5. The immunogen is located within amino acids 30 - 80 of CXXC5.

Isotype: IgG

Application Details

Application Notes: CXXC5 antibody can be used for detection of CXXC5 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CXXC5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CXXC5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CXXC5

Target: CXXC5 (CXXC Finger Protein 5 (CXXC5))

Alternative Name: CXXC5 (CXXC5 Products)

Synonyms: 4930415K17Rik antibody, CF5 antibody, RINF antibody, WID antibody, CXXC finger 5 antibody, CXXC finger protein 5 antibody, Cxxc5 antibody, CXXC5 antibody

Background: CXXC5 Antibody: CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.

Molecular Weight: Predicted: 25, 35 kDa

Observed: 25, 35 kDa

Gene ID: 51523

NCBI Accession: NP_057547

UniProt: Q7LFL8