LRRTM4 antibody (AA 350-400)

Catalog No. ABIN6991484

Product Details anti-LRRTM4 Antibody

Target: LRRTM4 (Leucine Rich Repeat Transmembrane Neuronal 4 (LRRTM4))

Binding Specificity: AA 350-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRTM4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: At least two isoforms of LRRTM4 are known to exist, this antibody will both isoforms. LRRTM4 antibody is predicted to not cross-react with other LRRTM family members.

Purification: LRRTM4 Antibody is affinity chromatography purified via peptide column.

Immunogen: LRRTM4 antibody was raised against a 16 amino acid synthetic peptide near the center of human LRRTM4. The immunogen is located within amino acids 350 - 400 of LRRTM4.

Isotype: IgG

Application Details

Application Notes: LRRTM4 antibody can be used for detection of LRRTM4 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: LRRTM4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: LRRTM4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LRRTM4

Target: LRRTM4 (Leucine Rich Repeat Transmembrane Neuronal 4 (LRRTM4))

Alternative Name: LRRTM4 (LRRTM4 Products)

Synonyms: 7530419J18Rik antibody, A230052N11 antibody, RGD1560707 antibody, DKFZp459D155 antibody, leucine rich repeat transmembrane neuronal 4 antibody, LRRTM4 antibody, Lrrtm4 antibody, lrrtm4 antibody

Background: LRRTM4 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Little is known about the function of LRRTM4, in mouse, it is expressed in the limb mesenchyme, neural tube, caudal mesoderm and in three distinct regions of the head. Later expression occurs in a subset of the developing sclerotome. Its similarity to other LRRTM family members suggests that LRRTM4 may also play a role in the development and maintenance of the vertebrate nervous system.

Gene ID: 80059

NCBI Accession: NP_001128217

UniProt: Q86VH4

Pathways: Synaptic Membrane