OGFOD2 antibody is predicted to not cross-react with other TPA1 protein family members. At least three isoforms are known to exist, this antibody will only detect the two larger isoforms.
Purification
OGFOD2 Antibody is affinity chromatography purified via peptide column.
Immunogen
OGFOD2 antibody was raised against a 17 amino acid synthetic peptide near the center of human OGFOD2. The immunogen is located within amino acids 140 - 190 of OGFOD2.
OGFOD2
Reactivity: Rat
WB, FACS, IF (cc), IF (p)
Host: Rabbit
Polyclonal
Alexa Fluor 750
Application Notes
OGFOD2 antibody can be used for detection of OGFOD2 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
OGFOD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C,4 °C
Storage Comment
OGFOD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
OGFOD2
(2-Oxoglutarate and Iron-Dependent Oxygenase Domain Containing 2 (OGFOD2))
OGFOD2 Antibody: OGFOD2 is a member of the 2-OG-Fe(II) dioxygenase family which plays an important role in ischemic survival and stress. Like the related protein OGFOD1, OGFOD2 is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. Little is known about the function of OGFOD2, but its similarity to OGFOD1 suggests that it is a novel stress granule component that may play an important proapoptotic role in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.