PALM3 antibody (N-Term)

Catalog No. ABIN6991570

Product Details anti-PALM3 Antibody

Target: PALM3 (Paralemmin 3 (PALM3))

Binding Specificity: AA 50-100, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PALM3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: At least two isoforms of Paralemmin3 are known to exist, this antibody will only detect the longer isoform

Purification: Paralemmin3 Antibody is affinity chromatography purified via peptide column.

Immunogen: Paralemmin3 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human Paralemmin3. The immunogen is located within amino acids 50 - 100 of Paralemmin3.

Isotype: IgG

Application Details

Application Notes: Paralemmin3 antibody can be used for detection of Paralemmin3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Paralemmin3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: Paralemmin3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PALM3

Target: PALM3 (Paralemmin 3 (PALM3))

Alternative Name: Paralemmin3 (PALM3 Products)

Synonyms: 4432412L15Rik antibody, AL024300 antibody, paralemmin 3 antibody, xlgv7 gene product antibody, PALM3 antibody, Palm3 antibody, palm3 antibody

Background: Paralemmin3 Antibody: Paralemmin3 is a recently identified protein that associates with the single immunoglobulin IL-1 receptor-related molecule (SIGIRR), a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Silencing of Paralemmin3 expression by RNAi inhibited the release of inflammatory cytokines in A549 cells after stimulation with lipopolysaccharide (LPS), suggesting Paralemmin3 may function as an adaptor in the LPS-TLR4 signaling pathway.

Gene ID: 342979

NCBI Accession: NP_001138500

UniProt: A6NDB9