NSRP1 antibody (C-Term)

Catalog No. ABIN6991591

Product Details anti-NSRP1 Antibody

Target: NSRP1 (Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))

Binding Specificity: AA 430-480, C-Term

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This NSRP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: At least three isoforms are known to exist, this antibody will detect all three.

Purification: CCDC55 Antibody is affinity chromatography purified via peptide column.

Immunogen: CCDC55 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human CCDC55. The immunogen is located within amino acids 430 - 480 of CCDC55.

Isotype: IgY

Application Details

Application Notes: CCDC55 antibody can be used for detection of CCDC55 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CCDC55 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CCDC55 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NSRP1

Target: NSRP1 (Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))

Alternative Name: CCDC55 (NSRP1 Products)

Synonyms: 8030451K07 antibody, AI851076 antibody, AL022898 antibody, NSpr70 antibody, NSrp70 antibody, Nsrp1 antibody, CCDC55 antibody, HSPC095 antibody, Ccdc55 antibody, RGD1309863 antibody, fc14d05 antibody, wu:fc14d05 antibody, zgc:152777 antibody, nuclear speckle regulatory protein 1 antibody, nuclear speckle splicing regulatory protein 1 antibody, Nsrp1 antibody, NSRP1 antibody, nsrp1 antibody

Background: CCDC55 Antibody: CCDC55, also known as Nuclear speckle-related protein 70 (NSrp70), was initially identified by the NIH Mammalian Gene Collection. Nuclear speckles are known to be the storage sites of mRNA splicing regulators. CCDC55 has been suggested to modulate alternative pre-mRNA splicing in vivo. It co-localizes and physically interacts with the SR proteins SC35 and ASF/SF2, essential splicing factors which are required for constitutive splicing and can regulate alternative mRNA splicing. Loss of CCDC55 in mice leads to early embryonic lethality highlights the importance of the functional role of CCDC55.

Gene ID: 84081

NCBI Accession: NP_115517

UniProt: Q9H0G5