DBX2 antibody (N-Term)

Catalog No. ABIN6991695

Product Details anti-DBX2 Antibody

Target: DBX2 (Eveloping Brain Homeobox 2 (DBX2))

Binding Specificity: AA 30-80, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DBX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: DBX2 antibody is human specific. At least two isoforms of DBX2 are known to exist, this antibody will only detect the shortest isoform.

Purification: DBX2 Antibody is affinity chromatography purified via peptide column.

Immunogen: DBX2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human DBX2. The immunogen is located within amino acids 30 - 80 of DBX2.

Isotype: IgG

Application Details

Application Notes: DBX2 antibody can be used for detection of DBX2 by Western blot at 1 and 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: DBX2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: DBX2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for DBX2

Target: DBX2 (Eveloping Brain Homeobox 2 (DBX2))

Alternative Name: DBX2 (DBX2 Products)

Synonyms: CHoxE antibody, 9430056A22Rik antibody, 9630005K15 antibody, AI846217 antibody, Gm1229 antibody, developing brain homeobox 2 antibody, DBX2 antibody, Dbx2 antibody

Background: DBX2 Antibody: DBX2 is a member of the developing brain homeobox (DBX) protein family, but while the related protein DBX1 is expressed in various regions of the developing brain, DBX2 shows a more restricted pattern of expression in the brain, and is also expressed in some mesenchymal cells such as limb buds and tooth germs. It is thought that DBX1 and DBX2 promote the development of a subset of interneurons, some of which help mediate left-right coordination of locomotor activity. In Xenopus, DBX2 is involved in primary neurogenesis and early neural plate patterning, and is thought to act as a cross-repressive partner of NKX6-2 in the patterning of the ventral neural tube.

Gene ID: 440097

NCBI Accession: NP_001004329

UniProt: Q6ZNG2