VPS13B antibody (N-Term)

Catalog No. ABIN6991715

Product Details anti-VPS13B Antibody

Target: VPS13B (Vacuolar Protein Sorting 13 Homolog B (Yeast) (VPS13B))

Binding Specificity: AA 90-140, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS13B antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Specificity: At least five alternatively spliced transcript variants have been observed. COH1 detects two isoforms.

Purification: COH1 Antibody is affinity chromatography purified via peptide column.

Immunogen: COH1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human COH1. The immunogen is located within amino acids 90 - 140 of COH1.

Isotype: IgG

Application Details

Application Notes: COH1 antibody can be used for detection of COH1 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: COH1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: COH1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for VPS13B

Target: VPS13B (Vacuolar Protein Sorting 13 Homolog B (Yeast) (VPS13B))

Alternative Name: COH1 (VPS13B Products)

Synonyms: 1810042B05Rik antibody, 2310042E16Rik antibody, 4732488H20 antibody, C330002D13Rik antibody, C87206 antibody, Coh1 antibody, D230005K13 antibody, mKIAA0532 antibody, mKIAA5032 antibody, CHS1 antibody, COH1 antibody, Cohh1 antibody, vacuolar protein sorting 13 homolog B antibody, vacuolar protein sorting 13B antibody, VPS13B antibody, Vps13b antibody

Background: COH1 Antibody: COH1 (Cohen syndrome protein 1), also known as VPS13B (vacuolar protein sorting-associated protein 13B) or CHS1, belongs to the VPS13 family and may function in vesicle-mediated transport and sorting of proteins within the cell. COH1 is widely expressed and multiple alternatively spliced transcript variants have been observed. Mutations in this gene have been associated with Cohen syndrome. COH1 is a Golgi-localized peripheral membrane protein and plays a critical role in Golgi (re)assembly.

Gene ID: 157680

NCBI Accession: NP_056058

UniProt: Q7Z7G8