GRINA antibody is predicted to not cross-react with other members of the TMBIM family.
Purification
GRINA Antibody is affinity chromatography purified via peptide column.
Immunogen
Rabbit polyclonal GRINA antibody was raised against an 18 amino acid peptide near the center of human GRINA. The immunogen is located within amino acids 110 - 160 of GRINA.
HNRGW antibody, LFG1 antibody, NMDARA1 antibody, TMBIM3 antibody, 1110025J15Rik antibody, Lag antibody, glutamate ionotropic receptor NMDA type subunit associated protein 1 antibody, glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) antibody, GRINA antibody, Grina antibody
Background
GRINA Antibody: The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein), TMBIM2/LFG (life guard), TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1), TMBIM4/GAAP (Golgi anti-apoptotic-associated protein), and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein). They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.