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FOXP3 antibody (C-Term)

FOXP3 Reactivity: Human, Mouse, Rat WB, ELISA, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991807
  • Target See all FOXP3 Antibodies
    FOXP3 (Forkhead Box P3 (FOXP3))
    Binding Specificity
    • 21
    • 16
    • 15
    • 10
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 149
    • 108
    • 43
    • 25
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 109
    • 57
    • 11
    • 2
    Rabbit
    Clonality
    • 110
    • 69
    Polyclonal
    Conjugate
    • 82
    • 18
    • 12
    • 12
    • 11
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This FOXP3 antibody is un-conjugated
    Application
    • 125
    • 80
    • 67
    • 37
    • 36
    • 27
    • 27
    • 16
    • 16
    • 15
    • 9
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    FOXP3 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Rabbit polyclonal FOXP3 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FOXP3. The immunogen is located within the last 50 amino acids of FOXP3.
    Isotype
    IgG
    Top Product
    Discover our top product FOXP3 Primary Antibody
  • Application Notes
    FOXP3 antibody can be used for detection of FOXP3 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    FOXP3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    FOXP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    FOXP3 (Forkhead Box P3 (FOXP3))
    Alternative Name
    FOXP3 (FOXP3 Products)
    Synonyms
    foxp3 antibody, FOXP3 antibody, AIID antibody, DIETER antibody, IPEX antibody, PIDX antibody, XPID antibody, JM2 antibody, scurfin antibody, sf antibody, RGD1562112 antibody, forkhead box P3 antibody, forkhead box P3a antibody, forkhead box P3 L homeolog antibody, FOXP3 antibody, foxp3a antibody, foxp3 antibody, foxp3.L antibody, Foxp3 antibody
    Background
    FOXP3 Antibody: FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
    Molecular Weight
    Predicted: 47 kDa
    Gene ID
    50943
    NCBI Accession
    NP_054728
    UniProt
    Q9BZS1
    Pathways
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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