FHIT antibody (C-Term)

Catalog No. ABIN6991896

The Rabbit Polyclonal anti-FHIT antibody (ABIN6991896) specifically detects FHIT in ELISA, WB and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for FHIT antibody (C-Term) (ABIN6991896)

Target: FHIT (Fragile Histidine Triad (FHIT))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FHIT antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-FHIT Antibody

Binding Specificity: C-Term

Specificity: FHIT antibody is human and mouse reactive.

Purification: FHIT Antibody is affinity chromatography purified via peptide column.

Immunogen: FHIT antibody was raised against an 18 amino acid peptide near the carboxy terminus of human FHIT. The immunogen is located within the last 50 amino acids of FHIT .

Isotype: IgG

Application Details

Application Notes: FHIT antibody can be used for detection of FHIT by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: FHIT Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: FHIT antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for FHIT

Target: FHIT (Fragile Histidine Triad (FHIT))

Alternative Name: FHIT

Background: FHIT is member of the histidine triad gene family and is a diadenosine involved in purine metabolism (1). FHIT is also thought to be a tumor suppressor gene and is involved in multiple apoptotic pathways (1,2). The FHIT gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene (3). Aberrant transcripts from this gene have been found in multiple carcinomas (4).

Molecular Weight: Predicted: 16 kDa

Observed: 15kDa

Gene ID: 2272

NCBI Accession: NP_002003

UniProt: P49789