DPF3 antibody (C-Term)

Catalog No. ABIN6991927

Product Details anti-DPF3 Antibody

Target: DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))

Binding Specificity: AA 220-270, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: DPF3 antibody is human and mouse reactive. Multiple isoforms of DPF3 are known to exist.

Purification: DPF3 antibody is affinity chromatography purified via peptide column.

Immunogen: DPF3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DPF3. The immunogen is located within amino acids 220 - 270 of DPF3.

Isotype: IgG

Application Details

Application Notes: DPF3 antibody can be used for detection of DPF3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: DPF3 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: DPF3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for DPF3

Target: DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))

Alternative Name: DPF3 (DPF3 Products)

Synonyms: BAF45C antibody, CERD4 antibody, 2810403B03Rik antibody, 6530402L11Rik antibody, C78788 antibody, cer-d4 antibody, si:ch211-268e23.1 antibody, wu:fj43h12 antibody, double PHD fingers 3 antibody, D4, zinc and double PHD fingers, family 3 antibody, DPF3 antibody, Dpf3 antibody, dpf3 antibody

Background: The DPF3 protein, also known as Cerd4, is a member of the d4 gene family of transcription modulators that also includes DPF1/Neud4 and DPF2/Requiem (1). DPF3 has been shown to be a epigenetic key factor for heart and muscle development and can bind to methylated and acetylated lysine residues of histone 3 and 4, suggesting that DPF3 may play a role in recruiting chromatin remodeling complexes to acetylated histones (2). Two isoforms of DPF3, DPF3a and DPF3b, are required as transcriptional co-activators in SWI/SNF complex-dependent activation of the NF-kappaB RelA/p50 heterodimer (3).

Molecular Weight: Predicted: 39 kDa

Observed: 50 kDa

Gene ID: 8110

NCBI Accession: NP_036206

UniProt: Q92784