GLIPR1L1 antibody (N-Term)

Catalog No. ABIN6991950

Product Details anti-GLIPR1L1 Antibody

Target: GLIPR1L1 (GLI Pathogenesis-Related 1 Like 1 (GLIPR1L1))

Binding Specificity: AA 20-70, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIPR1L1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: GLIPR1L1 antibody is human specific. At least two isoforms of GLIPR1L1 are known to exist, this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.

Purification: GLIPR1L1 antibody is affinity chromatography purified via peptide column.

Immunogen: GLIPR1L1 antibody was raised against an 18 amino acid peptide near the amino terminus of human GLIPR1L1 . The immunogen is located within amino acids 20 - 70 of GLIPR1L1.

Isotype: IgG

Application Details

Application Notes: GLIPR1L1 antibody can be used for detection of GLIPR1L1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: GLIPR1L1 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: GLIPR1L1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for GLIPR1L1

Target: GLIPR1L1 (GLI Pathogenesis-Related 1 Like 1 (GLIPR1L1))

Alternative Name: GLIPR1L1 (GLIPR1L1 Products)

Synonyms: 1700011E04Rik antibody, ALKN2972 antibody, PRO7434 antibody, GLI pathogenesis-related 1 like 1 antibody, GLI pathogenesis related 1 like 1 antibody, Glipr1l1 antibody, GLIPR1L1 antibody

Background: The GLIPR1-like 1 protein (GLIPR1L1) gene is part of a p53 target gene cluster that includes the related proteins GLIPR1 and GLIPR1L2 (1). GLIPR1L1 is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (2). GLIPR1 is a tumor suppressor whose expression is regulated by p53 (3). Unlike GLIPR1, GLIPR1L1 is expressed primarily in the testis and is thought to be involved in the binding of sperm to the oocyte complex (4).

Molecular Weight: Predicted: 26 kDa

Observed: 23 kDa

Gene ID: 256710

NCBI Accession: NP_689992

UniProt: Q6UWM5