MYH3 antibody (N-Term)

Catalog No. ABIN6992102

Product Details anti-MYH3 Antibody

Target: MYH3 (Myosin Heavy Chain 3, Skeletal Muscle, Embryonic (MYH3))

Binding Specificity: AA 30-80, N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYH3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: MYH3 antibody is human, mouse and rat reactive. MYH3 antibody is predicted to not cross-react with other members of the myosin heavy chain family.

Purification: MYH3 antibody is affinity chromatography purified via peptide column.

Immunogen: MYH3 antibody was raised against a 19 amino acid peptide near the amino terminus of human MYH3. The immunogen is located within amino acids 30 - 80 of MYH3.

Isotype: IgG

Application Details

Application Notes: MYH3 antibody can be used for detection of MYH3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: MYH3 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: MYH3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for MYH3

Target: MYH3 (Myosin Heavy Chain 3, Skeletal Muscle, Embryonic (MYH3))

Alternative Name: MYH3 (MYH3 Products)

Synonyms: HEMHC antibody, MYHC-EMB antibody, MYHSE1 antibody, SMHCE antibody, Myhse antibody, RNMHCG antibody, MyHC-emb antibody, Myhs-e antibody, MHC A antibody, MYH1B antibody, MYH3 antibody, Myosin-1B antibody, Myosin-3 antibody, myosin heavy chain 3 antibody, myosin, heavy polypeptide 3, skeletal muscle, embryonic antibody, Myosin-3 antibody, myosin, heavy chain 1D, skeletal muscle antibody, myosin, heavy chain 3, skeletal muscle, embryonic antibody, MYH3 antibody, Myh3 antibody, myo-3 antibody, MYH1D antibody

Background: Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells (1). MYH3 (myosin, heavy chain, skeletal muscle, embryonic) plays a significant role in skeletal muscle development (2) and is also essential for the proper morphology and function of the developing heart (3). Mutations in this gene have been associated with Freeman-Sheldon syndrome and Sheldon-Hall syndrome (4).

Molecular Weight: Predicted: 240 kDa

Observed: 245 kDa

Gene ID: 4621

NCBI Accession: NP_002461

UniProt: P11055