DNAJA4 antibody is human, mouse, and rat reactive. At least three isoforms of DNAJA4 are known to exist, this antibody will detect all three isoforms.
Purification
DNAJA4 antibody is affinity chromatography purified via peptide column.
Immunogen
DNAJA4 antibody was raised against a 15 amino acid peptide near the center of human DNAJA4. The immunogen is located within amino acids 210 - 260 of DNAJA4.
MGC52928 antibody, MST104 antibody, MSTP104 antibody, PRO1472 antibody, 1110021L12Rik antibody, AV358213 antibody, Dj4 antibody, Hsj4 antibody, mmDjA4 antibody, DnaJ (Hsp40) homolog, subfamily A, member 4, gene 2 S homeolog antibody, DnaJ heat shock protein family (Hsp40) member A4 antibody, dnaja4.2.S antibody, DNAJA4 antibody, Dnaja4 antibody
Background
The DNAJA4 protein is the mammalian homolog of the chaperone HSP40 (1) and acts as a co-chaperone with the heat shock protein HSP70 (2). DNAJA4 is highly expressed in heart and testis, accounting for approximately 1 % of total protein in mouse heart (2). DNAJA4 is also regulated by the sterol regulatory element binding transcription factor 2 (SREBF2) and plays a role in the synthesis of cholesterol (3).