GZMB antibody (AA 21-247)

Catalog No. ABIN7425959

The Mouse Monoclonal anti-GZMB antibody has been validated for WB. It is suitable to detect GZMB in samples from Human.

Quick Overview for GZMB antibody (AA 21-247) (ABIN7425959)

Target: GZMB (Granzyme B (GZMB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GZMB antibody is un-conjugated

Application: Western Blotting (WB)

Clone: D2

Product Details anti-GZMB Antibody

Binding Specificity: AA 21-247

Purpose: Monoclonal Antibody to Granzyme B (GZMB)

Specificity: The antibody is a mouse monoclonal antibody raised against GZMB. It has been selected for its ability to recognize GZMB in immunohistochemical staining and western blotting.

Purification: Protein A + Protein G affinity chromatography

Immunogen: Recombinant Granzyme B (GZMB) corresdonding to Ile21~Tyr247 with N-terminal His Tag

Isotype: IgG2b kappa

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for GZMB

Target: GZMB (Granzyme B (GZMB))

Alternative Name: GZMB

Background: GZM-B, HLP, CTLA1, CCPI, CGL1, CSP-B, CSPB, CTSGL1, SECT, Granzyme 2, Cytotoxic T-Lymphocyte-Associated Serine Esterase 1, Fragmentin 2, Cytotoxic Serine Protease B

UniProt: P10144

Pathways: Apoptosis, Caspase Cascade in Apoptosis