CRTAM antibody

Catalog No. ABIN7234933

Product Details anti-CRTAM Antibody

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTAM antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human CRTAM

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRTAM

Target: CRTAM (Cytotoxic and Regulatory T Cell Molecule (CRTAM))

Alternative Name: CRTAM (CRTAM Products)

Synonyms: TAD antibody, cTADS antibody, MGC82176 antibody, CRTAM antibody, CD355 antibody, cytotoxic and regulatory T-cell molecule antibody, cytotoxic and regulatory T-cell molecule L homeolog antibody, cytotoxic and regulatory T cell molecule antibody, CRTAM antibody, crtam.L antibody, Crtam antibody

Background: The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A, MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Molecular Weight:

Observed_MW: Refer to Figures

Calculated_MW: 45 kDa

UniProt: O95727

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation