APLF antibody

Catalog No. ABIN7235880

Product Details anti-APLF Antibody

Target: APLF (Aprataxin and PNKP Like Factor (APLF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLF antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human APLF

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for APLF

Target: APLF (Aprataxin and PNKP Like Factor (APLF))

Alternative Name: APLF (APLF Products)

Synonyms: apfl antibody, palf antibody, xip1 antibody, APLF antibody, C2orf13 antibody, DKFZp459J1223 antibody, APFL antibody, PALF antibody, Xip1 antibody, 2010301N04Rik antibody, AI452191 antibody, RGD1565557 antibody, aprataxin and PNKP like factor antibody, APLF antibody, aplf antibody, Aplf antibody

Background: C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro.

UniProt: Q8IW19

Pathways: DNA Damage Repair