FCAR antibody

Catalog No. ABIN7241318

Product Details anti-FCAR Antibody

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCAR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human FCAR

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FCAR

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Alternative Name: CD89 (FCAR Products)

Synonyms: CD89 antibody, Fc fragment of IgA receptor antibody, Fc fragment of IgA, receptor for antibody, FCAR antibody

Background: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 32 kDa

UniProt: P24071