PAX5 antibody

Catalog No. ABIN7247924

Product Details anti-PAX5 Antibody

Target: PAX5 (Paired Box 5 (PAX5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human PAX5

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: PAX5 (PAX5 Products)

Synonyms: PAX5 antibody, BSAP antibody, Pax-5 antibody, pax5-a antibody, RGD1565236 antibody, EBB-1 antibody, KLP antibody, Pax[Zf-b] antibody, noi antibody, pax2.1 antibody, pax2a antibody, paxzf-b antibody, paired box 5 antibody, paired box 5 L homeolog antibody, PAX5 antibody, pax5.L antibody, Pax5 antibody, pax5 antibody

Background: PAX5,also named B-cell specific activator protein (BSAP),is a member of the highly conserved paired box (PAX)-domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B,pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL ( B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL,PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members.

UniProt: Q02548