DPPA4 antibody

Catalog No. ABIN7248092

Product Details anti-DPPA4 Antibody

Target: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPPA4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human DPPA4

Isotype: IgG

Application Details

Application Notes: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.56 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DPPA4

Target: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Alternative Name: DPPA4 (DPPA4 Products)

Synonyms: 2410091M23Rik antibody, C76608 antibody, ECAT15-1 antibody, DPPA4 antibody, Dppa4 antibody, developmental pluripotency associated 4 antibody, DppA4 antibody, peptide ABC transporter substrate-binding protein antibody, dipeptide ABC transport system, substrate-binding protein antibody, similar to developmental pluripotency associated 4 isoform 1 antibody, DPPA4 antibody, Dppa4 antibody, dppA4 antibody, HVO_RS14920 antibody, LOC100360556 antibody, LOC683300 antibody

Background: This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

UniProt: Q7L190