C14orf2 antibody

Catalog No. ABIN7248334

Product Details anti-C14orf2 Antibody

Target: C14orf2 (Chromosome 14 Open Reading Frame 2 (C14orf2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C14orf2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human C14orf2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for C14orf2

Target: C14orf2 (Chromosome 14 Open Reading Frame 2 (C14orf2))

Alternative Name: C14orf2 (C14orf2 Products)

Synonyms: MP68 antibody, PLPM antibody, MLQ antibody, 9430003J03Rik antibody, AU043134 antibody, AV124504 antibody, Mp68 antibody, chromosome 14 open reading frame 2 antibody, chromosome 21 open reading frame, human C14orf2 antibody, RIKEN cDNA 2010107E04 gene antibody, C14orf2 antibody, C21H14orf2 antibody, 2010107E04Rik antibody

Background: C14orf2, also known as MP68, MP68 is a 58 amino acid mitochondrial protein that belongs to the small mitochondrial proteolipid family. The gene encoding MP68 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 7 kDa

UniProt: P56378