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NeuN antibody

RBFOX3 Reactivity: Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7249822
  • Target See all NeuN (RBFOX3) Antibodies
    NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))
    Reactivity
    • 53
    • 43
    • 37
    • 16
    • 4
    • 3
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 41
    • 15
    • 2
    Rabbit
    Clonality
    • 31
    • 27
    Polyclonal
    Conjugate
    • 27
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NeuN antibody is un-conjugated
    Application
    • 36
    • 19
    • 18
    • 15
    • 14
    • 13
    • 11
    • 11
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to NeuN
    Isotype
    IgG
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  • Application Notes
    WB 1:500-1:2000, IHC 1:300-1:800
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))
    Alternative Name
    RBFOX3 (RBFOX3 Products)
    Synonyms
    FOX-3 antibody, FOX3 antibody, HRNBP3 antibody, NEUN antibody, Fox-3 antibody, Hrnbp3 antibody, NeuN antibody, Neuna60 antibody, Neun antibody, RGD1560070 antibody, RNA binding fox-1 homolog 3 antibody, RNA binding protein, fox-1 homolog (C. elegans) 3 antibody, RNA binding protein, fox-1 homolog 3 antibody, RBFOX3 antibody, Rbfox3 antibody
    Background
    Immunoprecipitation and mass spectrometry of the two major NeuN species at 45-50 kDa identified both as the RNA binding protein Rbfox3 (a member of the Fox family of alternative splicing factors), confirming and extending the identification of the 45 kDa band as Rbfox3. Mapping of the anti-NeuN reactive epitopes in both R3hdm2 and Rbfox3 reveals a common proline- and glutamine-rich domain that lies at the N-terminus of the Rbfox3 protein. Nuclear Rbfox3 isoforms can also enhance the inclusion of cryptic exons in the Rbfox2 mRNA, resulting in nonsense-mediated decay of the message, thereby contributing to the negative regulation of Rbfox2 by Rbfox3 through a novel mechanism.
    Molecular Weight

    Observed_MW: 46-48 kDa

    Calculated_MW: 46-48 kDa

    UniProt
    Q8BIF2
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