STARD4 antibody

Catalog No. ABIN7254384

Product Details anti-STARD4 Antibody

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STARD4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human STARD4

Isotype: IgG

Application Details

Application Notes: IHC 1:25-1:100, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STARD4

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Alternative Name: STARD4 (STARD4 Products)

Synonyms: 4632419C16Rik antibody, 9030213J02Rik antibody, AA517649 antibody, AW324468 antibody, StAR related lipid transfer domain containing 4 antibody, StAR-related lipid transfer (START) domain containing 4 antibody, STARD4 antibody, Stard4 antibody

Background: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).

UniProt: Q96DR4