BIRC3 antibody

Catalog No. ABIN7255009

Product Details anti-BIRC3 Antibody

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC3 antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human BIRC3 (NP_001156.1).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BIRC3

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Alternative Name: BIRC3 (BIRC3 Products)

Synonyms: AIP1 antibody, API2 antibody, CIAP2 antibody, HAIP1 antibody, HIAP1 antibody, MALT2 antibody, MIHC antibody, RNF49 antibody, c-IAP2 antibody, Api1 antibody, Api2 antibody, IAP1 antibody, IAP2 antibody, MIHB antibody, Birc2 antibody, HIAP2 antibody, MIAP1 antibody, MIAP2 antibody, cIAP1 antibody, cIAP2 antibody, cIAP-1 antibody, cIAP-2 antibody, AW107670 antibody, BIRC2 antibody, baculoviral IAP repeat containing 3 antibody, baculoviral IAP repeat-containing 3 antibody, baculoviral IAP repeat-containing protein 3 antibody, inhibitor of apoptosis protein-2 antibody, BIRC3 antibody, Birc3 antibody, LOC100399118 antibody, OpmnVgp074 antibody

Background: This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

Gene ID: 330

UniProt: Q13489

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades