GRK2 antibody
Quick Overview for GRK2 antibody (ABIN7259288)
Target
See all GRK2 (ADRBK1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Specificity
- This antibody ist KO validated.
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein of human ADRBK1 (NP_001610.2).
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Isotype
- IgG
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anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 398-640) antibody
ADRBK1 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 440-689) antibodyADRBK1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) antibodyKO Validated ADRBK1 Reactivity: Human WB, IHC (p), IF, ICC, IP, FACS Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) antibodyADRBK1 Reactivity: Human, Mouse, Rat, Monkey WB, ELISA, IHC, ICC Host: Mouse Monoclonal 3F8 unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (Internal Region) antibodyADRBK1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 633-660), (C-Term) antibodyADRBK1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB0982 unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) antibodyADRBK1 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (N-Term) antibodyADRBK1 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (AA 2-221) antibodyADRBK1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) antibodyADRBK1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB 1:500-1:2000 IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
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Alternative Name
- ADRBK1
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Background
- The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
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Molecular Weight
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Observed_MW: 80 kDa
Calculated_MW: 79 kDa
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Gene ID
- 156
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UniProt
- P25098
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
Target
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