BDNF antibody

Catalog No. ABIN7259787

This Mouse Monoclonal antibody specifically detects BDNF in WB. It exhibits reactivity toward Rat and Mouse.

Quick Overview for BDNF antibody (ABIN7259787)

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Reactivity: Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This BDNF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BDNF Antibody

Characteristics: Monoclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human BDNF

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BDNF

Target: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Alternative Name: BDNF

Background: This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.

Molecular Weight:

Observed_MW: 28 kDa

Calculated_MW: 27 kDa/28 kDa/29 kDa/31 kDa/37 kDa

Gene ID: 627

UniProt: P23560

Pathways: RTK Signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity