ALT antibody

Catalog No. ABIN7260667

Product Details anti-ALT Antibody

Target: ALT (Alanine Aminotransferase (ALT))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALT antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human GPT (NP_005300.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ALT

Target: ALT (Alanine Aminotransferase (ALT))

Alternative Name: GPT (ALT Products)

Synonyms: AAT1 antibody, ALT1 antibody, GPT1 antibody, GPT antibody, Gpt1 antibody, An11g02620 antibody, AO090003000164 antibody, 233.t00009 antibody, 24.t00016 antibody, 1300007J06Rik antibody, 2310022B03Rik antibody, ALT antibody, Gpt-1 antibody, AU021132 antibody, Dpagt2 antibody, Gnpta antibody, gpt antibody, ALANINE AMINOTRANSFERAS antibody, AtAlaAT1 antibody, AtAlaATc antibody, T13M22.3 antibody, T13M22_3 antibody, alanine aminotransferas antibody, glutamic--pyruvic transaminase antibody, glutamic-pyruvate transaminase (alanine aminotransferase) antibody, alanine aminotransferase antibody, alanine aminotransferase 1 antibody, glutamic pyruvic transaminase, soluble antibody, dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) antibody, alanine aminotransferase 2-like antibody, Alanine aminotransferase 1, mitochondrial antibody, GPT antibody, Gpt antibody, Tb927.1.3950 antibody, ANI_1_368094 antibody, AOR_1_284154 antibody, ALAT_1 antibody, ALAAT1 antibody, EHI_159710 antibody, EHI_096750 antibody, LOC5572541 antibody, ALAT antibody, AAT2 antibody, Dpagt1 antibody, LOC100537633 antibody, AlaAT1 antibody

Background: This gene encodes cytosolic alanine aminotransaminase 1 (ALT1), also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.

Gene ID: 2875

UniProt: P24298