POR antibody

Catalog No. ABIN7264193

Product Details anti-POR Antibody

Target: POR (P450 (Cytochrome) Oxidoreductase (POR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificity: This antibody ist KO validated.

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Grade: KO Validated

Immunogen: Recombinant fusion protein of human POR (NP_000932.3).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for POR

Target: POR (P450 (Cytochrome) Oxidoreductase (POR))

Alternative Name: POR (POR Products)

Synonyms: CPR antibody, CYPOR antibody, P450R antibody, POR antibody, CCR antibody, CG11567 antibody, DMR antibody, DmCPR antibody, Dmel\\CG11567 antibody, NCPR antibody, P450 antibody, cpr antibody, zgc:110032 antibody, npr antibody, xpor antibody, 4933424M13Rik antibody, PORCINO antibody, T5J17.90 antibody, T5J17_90 antibody, TFC C antibody, TUBULIN-FOLDING COFACTOR C antibody, cytochrome p450 oxidoreductase antibody, P450 (cytochrome) oxidoreductase antibody, ADP-ribosylation factor interacting protein 2 antibody, Cytochrome P450 reductase antibody, P450 (cytochrome) oxidoreductase a antibody, P450 (cytochrome) oxidoreductase L homeolog antibody, NADPH--cytochrome P450 reductase antibody, C-CAP/cofactor C-like domain-containing protein antibody, POR antibody, Arfip2 antibody, Por antibody, Cpr antibody, pora antibody, por.L antibody, LOC100406157 antibody, por antibody, LOC100619047 antibody

Background: This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Molecular Weight:

Observed_MW: 77 kDa

Calculated_MW: 76 kDa

Gene ID: 5447

UniProt: P16435

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome