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COX7A2L antibody

COX7A2L Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7264325
  • Target See all COX7A2L Antibodies
    COX7A2L (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))
    Reactivity
    Human, Mouse, Rat
    Host
    • 24
    • 2
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COX7A2L antibody is un-conjugated
    Application
    • 18
    • 15
    • 15
    • 2
    • 1
    Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human COX7A2L (NP_004709.2).
    Isotype
    IgG
    Top Product
    Discover our top product COX7A2L Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    COX7A2L (Cytochrome C Oxidase Subunit VIIa Polypeptide 2 Like (COX7A2L))
    Alternative Name
    COX7A2L (COX7A2L Products)
    Synonyms
    COX7AR antibody, COX7RP antibody, EB1 antibody, SIG81 antibody, SIG-81 antibody, Silg81 antibody, cytochrome c oxidase subunit 7A2 like antibody, cytochrome c oxidase subunit VIIa polypeptide 2-like antibody, COX7A2L antibody, Cox7a2l antibody
    Background
    Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.
    Molecular Weight

    Observed_MW: 13 kDa

    Calculated_MW: 12 kDa

    Gene ID
    9167
    UniProt
    O14548
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