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Src Family (pTyr416) antibody

Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7265222
  • Target
    Src Family
    Binding Specificity
    pTyr416
    Reactivity
    Human, Mouse, Rat
    Host
    • 2
    Rabbit
    Clonality
    • 2
    Polyclonal
    Conjugate
    • 2
    Un-conjugated
    Application
    • 2
    • 1
    Western Blotting (WB)
    Characteristics
    Phosphorylated antibody
    Purification
    Affinity purification
    Immunogen
    A phospho specific peptide corresponding to residues surrounding Y416 of human SRC Family
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Src Family
    Background
    This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
    Molecular Weight

    Observed_MW: 60 kDa

    Calculated_MW: 59 kDa/60 kDa

    Gene ID
    6714
    UniProt
    P12931
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