CACNA1S antibody (2nd Extracellular Loop, Domain 4)

Catalog No. ABIN7043004

Product Details anti-CACNA1S Antibody

Target: CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))

Binding Specificity: 2nd Extracellular Loop, AA 506-518, Domain 4

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1S antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Anti-Cav1.1 (CACNA1S) (extracellular) Antibody is directed against an extracellular epitope of the rat CaV1.1 channel. Anti-CaV1.1 (CACNA1S) (extracellular) Antibody (ABIN7043004, ABIN7044107 and ABIN7044108)) can be used in western blot and immunohistochemistry applications. The antibody recognizes an extracellular epitope and is thus ideal for detecting the channel in living cells. It has been designed to recognize CaV1.1 from rat, mouse and human samples.

Purification: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: CGNVDPDESARIS, corresponding to amino acid residues 506-518 of rat CaV1.1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.85 mg/mL

Buffer: Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Details for CACNA1S

Target: CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))

Alternative Name: CaV1.1 (CACNA1S) (CACNA1S Products)

Synonyms: CACNA1S antibody, cav1.1 antibody, ca(v)1.1 antibody, CACNL1A3 antibody, CCHL1A3 antibody, Cav1.1 antibody, HOKPP antibody, HOKPP1 antibody, MHS5 antibody, TTPP1 antibody, hypoPP antibody, AW493108 antibody, Cchl1a3 antibody, fmd antibody, mdg antibody, sj antibody, caV1.1 antibody, calcium voltage-gated channel subunit alpha1 S antibody, calcium channel, voltage-dependent, L type, alpha 1S subunit S homeolog antibody, calcium channel, voltage-dependent, L type, alpha 1S subunit antibody, CACNA1S antibody, cacna1s.S antibody, Cacna1s antibody

Background: Alternative names: CaV1.1 (CACNA1S), Voltage-dependent L-type calcium channel subunit alpha1S, CACH1, CACN1, CACH1B, CACNL1A3

Gene ID: 682930

NCBI Accession: NM_000069

UniProt: Q02485

Pathways: Skeletal Muscle Fiber Development