Recombinant MAPT antibody

Catalog No. ABIN7072364

The Mouse Monoclonal anti-MAPT antibody is suitable to detect MAPT in samples from Human, Mouse, Rat and Sheep. It has been validated for IF and IEM.

Quick Overview for Recombinant MAPT antibody (ABIN7072364)

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat, Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAPT antibody is un-conjugated

Application: Immunofluorescence (IF), Immunoelectron Microscopy (IEM)

Clone: Tau-5

Product Details anti-MAPT Antibody

Purpose: Anti-tau [Tau-5], Mouse IgG1, kappa

Specificity:

This antibody binds to sequence 210-241 of tau protein.

Application Notes original Clone: This antibody binds to tau in a phosphorylation independent manner. Tau proteins are abundant in the central nervous system and stabilize micrtubules. Immuno-staining can be affected by different fixation methods (see LoPresti et al. 1995).

Cross-Reactivity: Mouse, Rat, Sheep

Purification: Protein A affinity purified

Immunogen: Tau protein.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

OriginalSpeciesName: Mouse

OriginalFormat: IgG1

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for MAPT

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Alternative Name: tau

Background: MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103, microtubule-associated protein tau

Pathways: MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size