Abeta 1-40 antibody

Catalog No. ABIN7073042

Product Details anti-Abeta 1-40 Antibody

Target: Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Abeta 1-40 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Abeta40

Application Details

Application Notes: IHC/IF (M,R) 1:400-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-Abeta 1-40 antibody (ABIN7073042)

Liu, Cao, Lin, Tan, Zhao, Guo, Tan: "Enhancement of Fear Extinction Memory and Resistance to Age-Related Cognitive Decline in Butyrylcholinesterase Knockout Mice and (R)-Bambuterol Treated Mice." in: Biology, Vol. 10, Issue 5, (2021) (PubMed).

Target Details for Abeta 1-40

Target: Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

Alternative Name: Amyloid beta 40 (Abeta 1-40 Products)

Synonyms: AAA antibody, ABETA antibody, ABPP antibody, AD1 antibody, APPI antibody, CTFgamma antibody, CVAP antibody, PN-II antibody, PN2 antibody, amyloid beta precursor protein antibody, APP antibody

Background: Most of autosomal dominant familial AD can be attributed to mutations in one of three genes: those encoding amyloid precursor protein (APP) and presenilins 1 and 2 Most mutations in the APP and presenilin genes increase the production of a small protein called Aβ42, which is the main component of senile plaques. Some of the mutations merely alter the ratio between Aβ42 and the other major forms-particularly Aβ40-without increasing Aβ42 levels.

Gene ID: 11820

NCBI Accession: NP_001185752

UniProt: P12023