Radixin antibody (AA 25-130) (Cy5.5)

Catalog No. ABIN704431

Product Details anti-Radixin Antibody (Cy5.5)

Target: Radixin (RDX)

Binding Specificity: AA 25-130

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Radixin antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Radixin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Radixin

Target: Radixin (RDX)

Alternative Name: Radixin (RDX Products)

Synonyms: DFNB24 antibody, AA516625 antibody, RDX antibody, radixin antibody, radixin L homeolog antibody, RDX antibody, Rdx antibody, rdx antibody, rdx.L antibody

Background:

Synonyms: ESP10, Hh-induced MATH and BTB domain-containing protein, HIB, Moesin-B, Protein roadkill, Radixin, rdx, CB567, CG12537, DFNB24, RADI_HUMAN.

Background: Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene ID: 5962

Pathways: Regulation of Actin Filament Polymerization, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome