EIF2S3 antibody

Catalog No. ABIN7073881

Product Details anti-EIF2S3 Antibody

Target: EIF2S3 (Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2S3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse EIF2G/EIF2S3

Application Details

Application Notes: WB (M,R) 1:500- 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for EIF2S3

Target: EIF2S3 (Eukaryotic Translation Initiation Factor 2, Subunit 3 Gamma, 52kDa (EIF2S3))

Alternative Name: EIF2G/EIF2S3 (EIF2S3 Products)

Synonyms: EIF2 antibody, EIF2G antibody, EIF2gamma antibody, eIF-2gA antibody, Su(var)3-9 antibody, fi03g03 antibody, wu:fi03g03 antibody, wu:fi37d04 antibody, zgc:63805 antibody, EIF2S3 antibody, eif2 antibody, eif2g antibody, eif2s3y antibody, eif2gamma antibody, Eif2g antibody, Eif2s3 antibody, PP42 antibody, ENSMUSG00000079297 antibody, eukaryotic translation initiation factor 2 subunit gamma antibody, eukaryotic translation initiation factor 2, subunit 3 gamma antibody, eukaryotic translation initiation factor 2 subunit gamma S homeolog antibody, putative eukaryotic translation initiation factor 2 subunit 3-like protein antibody, eukaryotic translation initiation factor 2 subunit 3 antibody, predicted pseudogene 2223 antibody, EIF2S3 antibody, eif2s3 antibody, eif2s3.S antibody, LOC738402 antibody, LOC100179499 antibody, LOC100624149 antibody, Eif2s3 antibody, Gm2223 antibody

Background: Interacts with GTP and initiator methionyl-tRNA, translation initiation factor eIF2 forms a ternary complex that binds the 40S ribosome and then scans an mRNA to select the AUG start codon for protein synthesis. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. EIF2S3 is the core subunit of the heterotrimeric eIF2 complex.

Molecular Weight: 51 kDa

Gene ID: 26905

UniProt: Q9Z0N1