Mitochondrial Inner Membrane Protease ATP23 Homolog (ATP23) antibody

Catalog No. ABIN7074637

Product Details

Target: Mitochondrial Inner Membrane Protease ATP23 Homolog (ATP23)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse XRCC6BP1/KUB3

Application Details

Application Notes: WB (M,R) 1: 1000-1: 2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details

Target: Mitochondrial Inner Membrane Protease ATP23 Homolog (ATP23)

Alternative Name: XRCC6BP1/KUB3

Background: The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 30 kDa

Gene ID: 68876

NCBI Accession: NP_081134

UniProt: Q9CWQ3