POLR3D antibody

Catalog No. ABIN7075141

Product Details anti-POLR3D Antibody

Target: POLR3D (Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR3D antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse POLR3D

Application Details

Application Notes: WB (M,R) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for POLR3D

Target: POLR3D (Polymerase (RNA) III (DNA Directed) Polypeptide D, 44kDa (POLR3D))

Alternative Name: POLR3D (POLR3D Products)

Synonyms: 2810426M17Rik antibody, 44kDa antibody, AI326118 antibody, AW489084 antibody, BN51T antibody, RPC4 antibody, TSBN51 antibody, RPC53 antibody, RNA polymerase III subunit D antibody, polymerase (RNA) III (DNA directed) polypeptide D antibody, Polr3d antibody, POLR3D antibody

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway .

Molecular Weight: 55 kDa

Gene ID: 67065

NCBI Accession: NP_001157554

UniProt: Q91WD1