PGRMC1 antibody
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- Target See all PGRMC1 Antibodies
- PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PGRMC1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse PGRMC1
- Top Product
- Discover our top product PGRMC1 Primary Antibody
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- Application Notes
- WB (H,M) 1:300-1:800
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- PGRMC1 (Progesterone Receptor Membrane Component 1 (PGRMC1))
- Alternative Name
- PGRMC1 (PGRMC1 Products)
- Synonyms
- MGC89150 antibody, wu:fa94d03 antibody, zgc:103577 antibody, DKFZp469D0815 antibody, HPR6.6 antibody, MPR antibody, AA415812 antibody, PPMR antibody, Vema antibody, 25-Dx antibody, 25Dx antibody, VEMA antibody, progesterone receptor membrane component 1 antibody, pgrmc1 antibody, PGRMC1 antibody, Pgrmc1 antibody
- Background
- Progesterone receptor membrane component 1 (PGRMC1) is a member of a multi-protein progesterone-binding complex. However, PGRMC1 shares homology with cytochrome b5-related proteins rather than hormone receptors . It is a heme binding protein with biding sites for Src homology (SH2) and SH3 domain-containing proteins . PGRMC1 is overexpressed in a variety of cancers, and thus represents an important biomarker for cancer progression and a potential target for anticancer drugs . In nonmalignant tissues, PGRMC1 is highly expressed in the liver and kidney.
- Molecular Weight
- 22 kDa
- Gene ID
- 53328
- NCBI Accession
- NP_058063
- UniProt
- O55022
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