PSMA8 antibody

Catalog No. ABIN7075232

Product Details anti-PSMA8 Antibody

Target: PSMA8 (Proteasome Subunit alpha 8 (PSMA8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA8 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse PSMA8

Application Details

Application Notes: WB (H,M,R) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PSMA8

Target: PSMA8 (Proteasome Subunit alpha 8 (PSMA8))

Alternative Name: PSMA8 (PSMA8 Products)

Synonyms: PSMA7L antibody, 2410072D24Rik antibody, psma7 antibody, zgc:77139 antibody, RGD1311659 antibody, proteasome subunit alpha 8 antibody, proteasome (prosome, macropain) subunit, alpha type, 8 antibody, PSMA8 antibody, Psma8 antibody, psma8 antibody

Background: Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. The proteasome is a protein complexe that degrades unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Required for 20S core proteasome assembly, essential for the degradation of meiotic proteins RAD51 and RPA1 at late prophase I and the progression of meiosis I during spermatogenesis. Localizes to the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I.

Molecular Weight: 28 kDa

Gene ID: 73677

NCBI Accession: NP_001157081

UniProt: Q9CWH6

Pathways: DNA Replication, Synthesis of DNA